Comparing Nexgard and Nexgard Spectra

By | May 14, 2022
Nexgard VS Nexgard Spectra

Parasite protection for our canine companions is a greater headache than coronavirus for every other dog parent. Fleas, ticks, and worms like blood-sucking insects, cause never-ending troubles for our loved animals. What is more, the ever-evolving veterinary medicine industry is flooded with newer anti-parasitic treatments every now and then creating an obvious confusion among pet parents. You’re always in a dilemma about which one is better, the one you were using previously or the upgraded one from the same brand?

Nexgard and Nexgard Spectra is one such pair of treatments that creates uncertainty when it comes to selecting one between the two. This article provides detailed information and articulates key differences between these two brands.

Understanding the Brands

About Nexgard and Nexgard Spectra

NexGard is a palatable beef-flavored, monthly chewable treatment that protects dogs against fleas, ticks, and mites. It is known to work against different types of ticks including brown dog ticks, and paralysis ticks.

NexGard Spectra is a tasty beef-flavored, one a month chewable to offer protection against multiple parasites including fleas, ticks (brown dog ticks, and the paralysis ticks), heartworms, intestinal worms, and mites in a single chew.

What’s Common in Nexgard & Nexgard Spectra?

Nexgard is made of one active ingredient, whereas Nexgard Spectra has two constituents. Both these anti-parasitics have one ingredient in common,i.e., afoxolaner. As a result, both efficiently protect against fleas, ticks, and mites.

Key Difference between Nexgard & Nexgard Spectra

Nexgard contains one ingredient, afoxolaner, and Nexgard Spectra is made with two active components, afoxolaner, and milbemycin oxime.

The major difference between the two is other than fleas, ticks, and mites, Nexgard Spectra (due to the extra ingredient milbemycin oxime) also protects against heartworms as well as intestinal worms such as roundworms and hookworms.

Comparative Analysis of Nexgard & Nexgard Spectra

Comparison of Basic Characteristics

The table below provides a comparison of some of the basic characteristics of these two brands:

Feature of Nexgard and Nexgard Spectra

Comparison of Parasite Protection

When it comes to parasite protection, Nexgard and Nexgard Spectra perform a bit differently due to the difference in their respective compositions. The table below compares the efficiency of each product against various pests.

Simparica & Simparica Trio – Comparison Table

Comparison of Disease Control

Due to their efficiency against various parasites, both Nexgard and Nexgard Spectra effectively treat and/or prevent different types of illnesses.

Comparison of Nexgard abd Nexgard Spectra


Through this article, now that you’ve gathered enough information about both Nexgard and Nexgard Spectra to make an educated choice between the two.

Just to give you a quick rewind, by virtue of an added constituent, milbemycin oxime, Nexgard Spectra gives additional protection against heartworms and intestinal worms. But, if you are only concerned about fleas, ticks, and mites, either of them will be equally efficient.

We’ll recommend consulting a veterinarian before administering any oral and/or topical treatment to your pet.