Nexgard Combo – A New All-In-One Cat Parasiticide Solution

By | June 6, 2022

Cat parents understand the joy that these furry four-legged-feline-friends bring to our lives. Because cats are naturally independent, they are often easier to care for when we share our homes with them. As a result, it’s vital for both you and your cat to keep it healthy and parasite-free.

Internal or external parasite infection in a cat is rather common over its lifetime. If left untreated, parasites can cause a number of problems for your cat, ranging from minor annoyance to life-threatening infections. Internal parasites (worms), in particular, can carry and transmit diseases to humans.

However, Nexgard Combo, a single broad-spectrum parasite control treatment, can now protect your cat and your family from these potentially deadly parasites. NexGard Combo is a systemic isoxazoline-based endectocide with esafoxolaner, eprinomectin, and praziquantel created specifically for cats. It’s not only about this ground-breaking topical solution. Nexgard Combo comes with a slew of features, benefits, and more! Keep on reading!

All-In-One Parasite Control Solution

NexGard Combo is a spot-on flea, tick, ear mite, roundworm, and tapeworm parasiticide that is marketed as the first and only broad-spectrum parasiticide for cats. The new treatment offers flea protection for one month and tick protection for five weeks against Ixodesricinus, the most prevalent tick on cats. Roundworms, Toxocaracati and Toxascarisleonina, hookworms, tapeworms, vesical worms, and ear mites are also treated.

Effective for Cats and Kittens

NexGard Combo is safe to use in kittens as young as eight weeks old and weighs 0.8 kg, giving it a good choice for most kittens’ first immunization. It comes in two sizes: small for kittens measuring 0.8 to 2.5 kg and large for adult cats weighing 2.5 to 7.5 kg. For cats weighing 7.5kg or more, a suitable combination of applicators should be used.

Eliminates both Internal & External Parasites

The active components in NexGard Combo target external and internal parasites in different ways.

Esafoxolaner is an ectoparasiticide that eliminates parasites that live on or in a cat’s skin, fur, or ear. It causes uncontrolled nervous system activity and death by disrupting the way messages pass between the parasite’s nerve cells (neurotransmission). Fleas and ticks are eradicated within 24 and 48 hours, respectively, after administration. Esafoxolaner kills fleas before they lay eggs, reducing infections in the home.

Endoparasiticides such as praziquantel and eprinomectin kill parasites that live inside the body of a cat. Praziquantel causes tapeworms to die by destroying their cell membranes. Eprinomectin interacts with roundworm nerve and muscle cells, paralyzing and killing them.

About the Benefits

The effectiveness of NexGard Combo was evaluated in both laboratory and field tests. NexGard Combo is valued for its efficacy in treating cats with (or at risk of) combination infections with ectoparasites, nematodes, and cestodes, according to the manufacturer.

An application of NexGard Combo for external parasites can treat flea and tick infestations for one month. It can also be used to treat ear and skin mite infestations, as well as to treat flea allergy dermatitis (an allergic skin reaction to flea bites).

NexGard Combo can be used to treat tapeworms, roundworms/hookworms, lungworms, and a roundworm that infects the internal organs when it comes to internal parasites. NexGard Combo can also be used to protect cats against heartworm disease for a month after each application.

  • Kills fleas before they lay eggs and is effective for one month.
  • Kills the most prevalent tick species in cats: Ixodesscapularis for one month and Ixodesricinus for five weeks.
  • Effective at preventing heartworm disease
  • Completely eradicate tapeworm and other intestinal worms
  • It exceeds the regulatory level of 90% for other internal parasite efficacy
  • Safe for cats and kittens as young as 8 weeks old and weighing at least 0.8kg

Administration and Dosage

NexGard COMBO is administered as a spot-on with a systemic mode of action and is simple to use, thanks to its innovative applicator.

Dosage Table:


A suitable combination of applicators should be used for cats weighing 7.5kg or more.

Bottom Line

Cats are self-sufficient and proud animals. They eat whenever they want and constantly groom themselves. They appear to live a tranquil and leisurely life. As a result, many cat parents overlook the fact that, like dogs, cats are susceptible to parasite infestation. To protect your feline buddy from parasites, you must grasp the importance of parasite prevention and treatment as a responsible cat parent. Consult a vet and discuss this revolutionary broad-spectrum treatment for your furry feline friend’s all-around protection.