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Advantage Multi (Advocate) Extra Large Dogs 55.1-88 lbs (Blue)
4.7/5
(301)
Advantage Multi (Advocate)

Advantage Multi (Advocate) Extra Large Dogs 55.1-88 lbs (Blue)

4.7/5
(301)
$61.27
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Select Size
  • 3 to 9lbs
  • 9 to 20lbs
  • 20 to 55lbs
  • 55 to 88lbs
Select Pack
  • 3 Doses
  • 6 Doses
  • 12 Doses
$61.27
$55.14

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  • Information
  • Key Benefits
  • Directions for Use
  • Safety
Information

Advantage Multi Blue for Extra Large Dogs: Monthly Topical Parasite Protection

Advantage Multi Blue is a topical solution that protects extra large dogs against multiple parasites, including heartworm disease, fleas, sarcoptic mange, and intestinal worms. This monthly treatment forgives if you forget the dosage, as you can treat your dog immediately and resume your monthly schedule when you are a few days late in dosage administration. Advantage Multi kills fleas through contact, so fleas do not have to bite your dog to get killed. This convenient topical solution is suitable for dogs and puppies aged at least 7 weeks and weighing between 55.1 & 88 lbs.

Advantage Multi Blue Coverage

With a mess-free application, Advantage Multi makes heartworm prevention for dogs easy. This monthly topical treatment:

  • Prevents heartworm disease caused by Dirofilaria immitis
  • Treats Dirofilaria immitis circulating microfilariae in heartworm-positive dogs
  • Kills adult fleas and treats flea infestations
  • Treats and controls sarcoptic mange
  • Treats and controls hookworms, roundworms, and whipworms

How does Advantage Multi Blue Work?

Advantage Multi Blue for Extra Large Dogs contains two active ingredients: Imidacloprid and moxidectin. When applied on the dog’s skin, imidacloprid spreads over the body and kills fleas on contact, so that fleas do not have to bite the dog to die. Moxidectin is absorbed into the body and keeps killing hookworms, roundworms, and whipworms all month long. Both ingredients work together to provide protection against sarcoptic mange.

Ingredients

Imidacloprid and Moxidectin

Key Benefits
Advantages Of Advantage Multi (Advocate)
  • Monthly treatment to protect dogs against multiple types of parasites
  • Convenient & mess-free topical application
  • Forgives if you forget: If you miss a dose, re-dose immediately and resume the monthly schedule
  • Kills fleas through contact, no biting required
  • Protects against heartworm disease, fleas, intestinal worms and sarcoptic mange
  • Suitable for dogs and puppies from 7 weeks of age, and having at least 3 lbs. of body weight
  • Available in different packs for weight-appropriate dosage
Directions for Use

Instructions To Use Advantage Multi (Advocate)

  • Weigh your dog and get the Advantage Multi pack that corresponds to their body weight.
  • Remove one dose applicator tube from the package.
  • Hold the tube in an upright position and remove the cap.
  • Turn the cap over and push the other end of the cap onto the tip of the tube.
  • Twist the cap to break the seal, and then remove the cap from the tube.
  • The dog should be standing for the application. Part the hair on the back of the dog between the shoulder blades until the skin is visible.
  • For dogs weighing up to 20 lbs.: Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades.
  • For dogs weighing more than 20 lbs.: Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at three or four spots, on the top of the backline from the base of the neck to the upper back, in an area that is inaccessible for licking. Do not apply an amount of solution to any one location that could run off the side of the dog.
  • For the first 30 minutes after application: Ensure that the dog cannot lick the product from the application sites on themselves or other treated animals.
  • In a multi-pet household, keep each treated dog separate from other treated dogs and pets for 30 minutes after application to prevent licking the application sites.

Packaging:

  • Advantage Multi for Dogs is available in four different sizes for a weight-appropriate dosage.
  • The packs are color-coded for easier identification.

Dosage:

Dog weight (lbs.) Dog size Pack color Volume (ml) Imidacloprid (mg) Moxidectin (mg)
3 – 9 Small Green 0.4 40 10
9.1 – 20 Medium Aqua 1.0 100 25
20.1 – 55 Large Red 2.5 250 62.5
55.1 – 88 Extra Large Blue 4.0 400 100
Safety
Advantage Multi (Advocate) Safety Measures
  • It is not for human use. Keep out of reach of children.
  • Do not administer this product orally.
  • Do not use it on cats.
  • Do not let children come in contact with application sites for two hours after application.
  • It is harmful if swallowed.
  • Avoid contact with your skin or clothing. If contact with skin or clothing occurs, take off contaminated clothing, wash the skin immediately and contact a poison control centre or a physician immediately for treatment advice.
  • Do not get it into the eyes. If contact with the eyes occurs, hold eyelids open and flush with water for 15 minutes. If eye irritation develops or persists, contact a physician.
  • Wash your hands thoroughly with soap and warm water after handling the product.

Precautions

  • Use with caution in avermectin-sensitive dogs.
  • Use with caution in sick, debilitated or underweight animals.
  • Consult a veterinarian before using it in breeding, pregnant or lactating dogs.
  • Dogs should be tested for existing heartworm infection prior to administration of Advantage Multi for dogs. At the discretion of a veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms.

Storage

  • Store at temperatures between 39°F (4°C) and 77°F (25°C), avoiding excess heat or cold.
Customer Review
Overall Rating

Star4.7/5

301 reviews
301 reviews
Sort By:
Luca
Good Pet Care Solution

Helps keep my pet feeling good and active. Easy to use and reliable.

Mar 06, 2026
Lucas
Dependable Pet Care Item

Makes caring for pets easier every day.

Feb 26, 2026
Jaclyn
5

Excellent, fast service.

Feb 24, 2026
Sophia
Helpful

Suits my little one perfectly

Feb 04, 2026
Stevenson
Broad coverage

Offers wide protection against multiple parasites

Jan 25, 2026
Have A Question?
Question:
Q:

Does this come in Pill form?

Answer:
A:

Advantage Multi is only available in a topical liquid formula.

Jan 08, 2026
Question:
Q:

What is the difference between advocate and advantage multi

Answer:
A:

Advocate and Advantage both are differently formulated topical monthly treatments. Advocate for Dogs contains imidacloprid and moxidectin and protects against fleas, heartworms, sarcoptic mange, ear mites and intestinal worms including roundworms, hookworms and whipworms. Advantage for Dogs contains imidacloprid hence protecting against fleas and chewing lice.

Jan 02, 2025
Advantage Multi (Advocate) Extra Large Dogs 55.1-88 lbs (Blue) 3 Doses
$61.27

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