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Frontline Plus for Dogs

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4.7/5
(248)

Starts From:

$31.57

Frontline Plus Small Dogs up to 22lbs (Orange)

Pack
Qty
Price
 
3 Doses
$31.57
6 Doses
$53.35

Frontline Plus Medium Dogs 23-44 lbs (Blue)

Pack
Qty
Price
 
3 Doses
$36.52
6 Doses
$66.22

Frontline Plus Large Dogs 45-88 lbs (Purple)

Pack
Qty
Price
 
3 Doses
$39.49
6 Doses
$72.16

Frontline Plus Extra Large Dogs over 89 lbs (Red)

Pack
Qty
Price
 
3 Doses
$42.46
6 Doses
$75.13
  • Information
  • Key Benefits
  • Directions for Use
  • Safety
  • FAQ
Information

Frontline Plus for Dogs: Monthly Topical Flea and Tick Treatment

Frontline Plus is a fast-acting and long-lasting topical parasite treatment for dogs and puppies aged 8 weeks and above, and weighing at least 5 lbs. It has been trusted by pet parents for years for the protection of their dogs against fleas and ticks. This monthly treatment is also effective against chewing lice and sarcoptic mange/mites infestations. Frontline Plus waterproof formula keeps working even if your dog gets wet (dogs should stay dry for 24 hours after application).

Frontline Plus coverage

Frontline Plus topical solution for dogs is convenient and easy to use. When applied monthly as directed, it:

  • Kills fleas, flea eggs and flea larvae and prevents all flea stages (eggs, larvae, pupae) from developing
  • Kills fleas, which may cause Flea Allergy Dermatitis (FAD)
  • Kills all life stages of ticks (larva, nymph and adult), including brown dog ticks, American dog ticks, lone star ticks, and deer ticks
  • Kills ticks that may transmit Lyme disease, Rocky Mountain spotted fever, haemobartonellosis, ehrlichiosis, babesiosis, anaplasmosis, and other tick-borne diseases
  • Eliminates chewing lice infestations
  • Aids in control of sarcoptic mange infestations

How does Frontline Plus work?

Frontline Plus contains fipronil and (S)-methoprene. These powerful ingredients spread from the single point of application and cover the dog’s entire coat. The ingredients localize in the hair, on the surface of the skin, and continuously get replenished onto the skin and coat. Parasites come into contact with the treated dog, and are killed quickly. Fleas and ticks do not have to bite your dog in order to die.

Ingredients

Fipronil and (S)-Methoprene

Key Benefits
Advantages Of Frontline Plus
  • Fast-acting and long-lasting flea and tick treatment for dogs
  • Convenient once-a-month topical application
  • Helps control fleas, ticks, chewing lice and sarcoptic mites
  • Kills ticks, including those that may transmit Lyme disease
  • Waterproof (24 hours after application): stays effective even after bathing, water immersion or exposure to sunlight
  • Suitable for dogs and puppies from 8 weeks of age, and having at least 5 lbs. of body weight
  • Available in different packs for weight-appropriate dosage
Directions for Use

Instructions To Use Frontline Plus

  • Weigh your dog and get the suitable Frontline Plus pack for your dog.
  • Remove the applicator from the pack. Hold it upright with the foil side towards you, and snap the tip.
  • Part your dog’s hair between the shoulder blades.
  • Place the applicator tip just above the skin and squeeze.
  • Apply the entire contents of the applicator in a single spot directly onto the dog’s skin.
  • Do not apply the product on top of your dog’s hair coat.
  • Ensure that your dog’s skin and coat are dry at the time of application, and remain dry for 24 hours after application.
  • Do not let your dog ingest the product.
  • Do not use more than one applicator per dog per month.

Packaging:

  • Frontline Plus for Dogs is available in four different sizes for a weight-appropriate dosage.
  • The packs are color-coded for easier identification.

Dosage

Dog weight (lbs.) Pack color Dosage (ml)
5 – 22 Orange 0.67
23 – 44 Blue 1.34
45 – 88 Purple 2.68
89 – 132 Red 4.02
Safety
Frontline Plus Safety Measures
  • This product is for external use in dogs only. Do not use it on cats, rabbits or other animals.
  • Read the entire label and follow the directions for use.
  • Avoid contact with the treated area until dry.
  • Do not apply it on dogs weighing less than 5 lbs or younger than 8 weeks of age.
  • Do not place unused product down any indoor or outdoor drain. Place it in the trash.
  • Do not reuse the container.
  • Wash your hands thoroughly with soap and water after handling the product and before eating, drinking, chewing gum, or using tobacco.
  • If swallowed, sip a glass of water if able to swallow. Call a poison control centre or doctor immediately for treatment advice.
  • If in the eyes, rinse slowly and gently with water for 15–20 minutes. Call a poison control centre or doctor for treatment advice.
  • If on skin or clothing, take off contaminated clothes and rinse the skin immediately with water for 15–20 minutes. Contact the poison control centre or doctor for treatment advice.

Storage

  • Do not store or use near heat or open flame.
  • Store unused product in original container, out of reach of children and animals.
FAQ

Frequently asked questions

1. Is Frontline Plus waterproof?

Yes. Frontline Plus stays effective even after the treated dog’s bathing, water immersion or exposure to sunlight. However, ensure that your dog is dry at the time you apply Frontline Plus and stays dry for 24 hours after application.

2. How often should I treat my dog with Frontline Plus?

Administer one dose of Frontline Plus flea and tick treatment to your dog once per month (every 30 days). Regular, year-round application helps provide uninterrupted flea and tick protection to dogs.

3. Can I use Frontline Plus on my pregnant dog?

Frontline Plus is approved for use in breeding, pregnant and lactating female dogs. Consult a veterinarian before using it if you are confused or need further guidance.

4. Does Frontline Plus kill flea eggs?

Yes. Frontline Plus kills fleas, flea eggs and flea larvae, and prevents all flea stages (eggs, larvae, pupae) from developing.

5. Is Frontline Plus safe for my puppy?

Frontline Plus is intended for use on dogs and puppies aged 8 weeks or older, and weighing at least 5 lbs.

6. Can I use Frontline Plus on my cat?

Frontline Plus for dogs or any dog treatments should never be used on cats. Opt for the cat-specific Frontline Plus option for your cat’s treatment.

7. Where can I buy Frontline Plus?

Frontline Plus for dogs is available at our online store, BestVetCare. You can buy this and other pet care products online from our store and take advantage of competitive prices and hassle-free order delivery.

Customer Review
Overall Rating

Star4.7/5

248 reviews
248 reviews
Sort By:
Natalie
Very Practical

A good product for regular pet maintenance.

Mar 05, 2026
George
Helpful Product for Pet Owners

A dependable choice for maintaining pet wellness.

Feb 25, 2026
Fern
5

Always pleased with my orders

Feb 19, 2026
George
Easy application

Pretty simple to use this, must buy!

Feb 10, 2026
David
Happy customer

Happy to buy this at discounted prices

Feb 03, 2026
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